Preprint
Proteome-wide Mendelian randomization study implicates inflammaging biomarkers in retinal vasculature, cardiometabolic diseases and longevity
Abstract
With the increasing proportion of elderly individuals, improving understanding of the biological mechanisms involved in healthy aging is of utmost importance. Retinal vascular complexity obtained from retinal fundus photographs, and evaluated as fractal dimension (ie, Df), a measure of the geometric pattern of the retinal vasculature, has recently emerged as a valuable indicator of diseases and aging processes. The purpose of our study was to …
Authors
Villaplana-Velasco A; Perrot N; Hang Y; Chong M; Trucco E; Nelson W; Petch J; Gerstein H; Parminder R; Yusuf S
DOI
10.1101/2024.07.13.24310153
Preprint server
medRxiv