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Protocol implementation during the COVID-19...
Journal article

Protocol implementation during the COVID-19 pandemic: experiences from a randomized trial of stress ulcer prophylaxis

Abstract

BackgroundDuring the COVID-19 pandemic, many intensive care units (ICUs) halted research to focus on COVID-19-specific studies.ObjectiveTo describe the conduct of an international randomized trial of stress ulcer prophylaxis (Re-Evaluating the Inhibition of Stress Erosions in the ICU [REVISE]) during the pandemic, addressing enrolment patterns, center engagement, informed consent processes, data collection, a COVID-specific substudy, patient …

Authors

Dennis B; Deane A; Lauzier F; Zytaruk N; Hardie M; Hammond N; Finfer S; Arabi Y; Marshall J; Saunders L

Journal

BMC Medical Research Methodology, Vol. 24, No. 1,

Publisher

Springer Nature

DOI

10.1186/s12874-024-02233-2

ISSN

1471-2288