Journal article
Amphotericin B-loaded natural latex dressing for treating Candida albicans wound infections using Galleria mellonella model
Abstract
Amphotericin B (AmB) is the gold standard for antifungal drugs. However, AmB systemic administration is restricted because of its side effects. Here, we report AmB loaded in natural rubber latex (NRL), a sustained delivery system with low toxicity, which stimulates angiogenesis, cell adhesion and accelerates wound healing. Physicochemical characterizations showed that AmB did not bind chemically to the polymeric matrix. Electronic and …
Authors
Herculano RD; Dos Reis CE; de Souza SMB; Pegorin Brasil GS; Scontri M; Kawakita S; Carvalho BG; Bebber CC; Su Y; de Sousa Abreu AP
Journal
Journal of Controlled Release, Vol. 365, , pp. 744–758
Publisher
Elsevier
Publication Date
January 2024
DOI
10.1016/j.jconrel.2023.12.010
ISSN
0168-3659