Journal article
Analysis of the Impact of Whole Blood and T-Cell Donor Chimerism after Allogeneic Stem Cell Transplant
Abstract
Background: Allogeneic stem cell transplant (alloSCT) is one of the few currently available therapies to cure acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Positive outcomes are dependent on engraftment of donor cells to provide hematopoiesis as well as a graft-versus-tumor effect. Measurement of whole blood (WB) and T-cell (TC) chimerism at routine intervals post alloSCT allows for monitoring of engraftment. Development of …
Authors
Radford M; Garcia-Horton A; Badami R; Jin E; Usmani NJ; Grafodatskaya D; McCready E; Khalaf D; Walker I; Leber B
Journal
Blood, Vol. 142, No. Supplement 1,
Publisher
American Society of Hematology
Publication Date
November 2, 2023
DOI
10.1182/blood-2023-187458
ISSN
0006-4971