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Constitutive expression of a gene encoding a...
Journal article

Constitutive expression of a gene encoding a polypeptide homologous to biologically active human platelet protein in Rous sarcoma virus-transformed fibroblasts.

Abstract

A molecular clone corresponding to a 1.2-kilobase mRNA enriched in Rous sarcoma virus-transformed chicken embryo fibroblasts (CEF) was identified by differential screening of a cDNA library. The induction of the cloned sequence (denoted pCEF-4) in CEF infected by the temperature-sensitive mutant NY72-4 Rous sarcoma virus is rapid and independent of protein synthesis. DNA sequencing of the 1.2-kilobase insert of CEF-4 revealed an open reading …

Authors

Bedard PA; Alcorta D; Simmons DL; Luk KC; Erikson RL

Journal

Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, No. 19, pp. 6715–6719

Publisher

Proceedings of the National Academy of Sciences

Publication Date

October 1987

DOI

10.1073/pnas.84.19.6715

ISSN

0027-8424