Journal article
It is time to improve the diagnostic workup of oropharyngeal cancer with circulating tumor HPV DNA: Systematic review and meta‐analysis
Abstract
The possibility of detecting circulating tumor HPV DNA (ctHPVDNA) in plasma in patients with oropharyngeal cancer has been demonstrated in several reports. However, these data are from small cohorts and available tests for detection of ctHPVDNA are not fully validated. The aim is to evaluate sensitivity, specificity, and accuracy of ctHPVDNA by ddPCR to define its efficacy in the clinical setting for the diagnosis of HPV + OPSCC. A …
Authors
Paolini F; Campo F; Iocca O; Manciocco V; De Virgilio A; De Pascale V; Moretto S; Dalfino G; Vidiri A; Blandino G
Journal
Head & Neck, Vol. 45, No. 11, pp. 2945–2954
Publisher
Wiley
Publication Date
November 2023
DOI
10.1002/hed.27515
ISSN
1043-3074