Journal article
Effect of Colchicine on the Risk of Perioperative Acute Kidney Injury: Clinical Protocol of a Substudy of the Colchicine for the Prevention of Perioperative Atrial Fibrillation Randomized Clinical Trial
Abstract
Background: Inflammation during and after surgery can lead to organ damage including acute kidney injury. Colchicine, an established inexpensive anti-inflammatory medication, may help to protect the organs from pro-inflammatory damage. This protocol describes a kidney substudy of the colchicine for the prevention of perioperative atrial fibrillation (COP-AF) study, which is testing the effect of colchicine versus placebo on the risk of atrial …
Authors
Garg AX; Cuerden M; Cata J; Chan MTV; Devereaux PJ; Fleischmann E; Grande AM; Kabon B; Landoni G; Maziak DE
Journal
Canadian Journal of Kidney Health and Disease, Vol. 10, ,
Publisher
SAGE Publications
Publication Date
January 2023
DOI
10.1177/20543581231185427
ISSN
2054-3581