Severely burned patient peripheral linage– CD34+ cells are inhibitory on the antimicrobial peptide production by human epidermal keratinocytes (133.10)

Abstract The importance of epidermal keratinocyte-produced antimicrobial peptides in the control of skin infections has been described. However, these peptides are not produced sufficiently in tissues surrounding the burn area. In this study, linage- CD34+ cells that infiltrated into burn area tissues were shown to be inhibitory on the antimicrobial peptide production by human epidermal keratinocytes (NHEK). Peripheral blood mononuclear cells …