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Tumor Necrosis Factor-alpha and its association...
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Tumor Necrosis Factor-alpha and its association with bipolar disorder: a systematic review and meta-analysis

Abstract

OBJECTIVE: The objective of this study is to conduct a systematic review and meta-analysis of the association between bipolar disorder (BD) and levels of Tumor Necrosis Factor-alpha (TNF-alpha) and its receptors. METHODS: A systematic review and meta-analysis was conducted for studies analyzing TNF-alpha and its receptors, according to the PRISMA guidelines. Studies evaluating protein and gene expression levels in peripheral blood or in …

Authors

McIntyre A; Mozafar D; Liang M; Kapczinski F; Wollenhaupt-Aguiar B

Volume

191

Pagination

pp. 634-652

Publisher

Elsevier

Publication Date

November 2025

DOI

10.1016/j.jpsychires.2025.09.077

Conference proceedings

Journal of Psychiatric Research

ISSN

0022-3956