Journal article
Crocetin Prevents Dexamethasone-Induced Insulin Resistance in Rats
Abstract
The main objective of the study was to examine whether crocetin, a natural product from Gardenia jaminoides Ellis, has beneficial effects on the state of insulin resistance induced by dexamethasone in a rat model. Measured using the oral glucose tolerance tests (OGTT), male Wistar rats treated with subcutaneous dexamethasone (0.08 mg/kg/d) for 6 weeks exhibited reduced insulin sensitivity at weeks 2 and 4 and impaired glucose tolerance at week …
Authors
Xi L; Qian Z; Shen X; Wen N; Zhang Y
Journal
Planta Medica, Vol. 71, No. 10, pp. 917–922
Publisher
Thieme
Publication Date
September 2005
DOI
10.1055/s-2005-871248
ISSN
0032-0943