Journal article
Initiation Dose of Allopurinol and the Risk of Severe Cutaneous Reactions in Older Adults With CKD: A Population-Based Cohort Study
Abstract
RATIONALE & OBJECTIVE: Allopurinol should be started at lower doses in patients with chronic kidney disease (CKD) to avoid adverse effects. We examined the risk of severe cutaneous reactions in older adults with CKD who were newly prescribed allopurinol at varied doses.
STUDY DESIGN: Population-based cohort study using linked health care databases.
Authors
Bathini L; Garg AX; Sontrop JM; Weir MA; Blake PG; Dixon SN; McArthur E; Muanda FT
Journal
American Journal of Kidney Diseases, Vol. 80, No. 6, pp. 730–739
Publisher
Elsevier
Publication Date
December 2022
DOI
10.1053/j.ajkd.2022.04.006
ISSN
0272-6386