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Rare neurovascular genetic and imaging markers...
Journal article

Rare neurovascular genetic and imaging markers across neurodegenerative diseases

Abstract

INTRODUCTION: Cerebral small vessel disease (SVD) is common in patients with cognitive impairment and neurodegenerative diseases such as Alzheimer's and Parkinson's. This study investigated the burden of magnetic resonance imaging (MRI)-based markers of SVD in patients with neurodegenerative diseases as a function of rare genetic variant carrier status. METHODS: The Ontario Neurodegenerative Disease Research Initiative study included 520 …

Authors

Dilliott AA; Berberian SA; Sunderland KM; Binns MA; Zimmer J; Ozzoude M; Scott CJM; Gao F; Lang AE; Breen DP

Journal

Alzheimer's & Dementia, Vol. 19, No. 12, pp. 5583–5595

Publisher

Wiley

Publication Date

December 2023

DOI

10.1002/alz.13316

ISSN

1552-5260