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Bioactivity of the cannabigerol cannabinoid and...
Journal article

Bioactivity of the cannabigerol cannabinoid and its analogues – the role of 3-dimensional conformation

Abstract

Cannabinoids are naturally occurring bioactive compounds with the potential to help treat chronic illnesses including epilepsy, Parkinson's disease, dementia and multiple sclerosis. Their general structures and efficient syntheses are well documented in the literature, yet their quantitative structure-activity relationships (QSARs), particularly 3-dimensional (3-D) conformation-specific bioactivities, are not fully resolved. Cannabigerol (CBG), …

Authors

Salha M; Adenusi H; Dupuis JH; Bodo E; Botta B; McKenzie I; Yada RY; Farrar DH; Magolan J; Tian KV

Journal

Organic & Biomolecular Chemistry, Vol. 21, No. 22, pp. 4683–4693

Publisher

Royal Society of Chemistry (RSC)

Publication Date

June 7, 2023

DOI

10.1039/d3ob00383c

ISSN

1477-0520