Journal article
DIFFERENTIAL EXPRESSION OF HEPATOCYTE GROWTH FACTOR IN LIVER, KIDNEY, LUNG, AND SPLEEN FOLLOWING BURN IN RATS
Abstract
Hepatocyte growth factor (HGF) plays a role as an organotropic factor for regeneration of injured organs. HGF is synthesized as an inactive single-chain precursor which is then converted to a biologically active heterodimeric form by proteolytic processing. Burn is the insult that results in hypovolemia which causes systemic organ injury. In this study, we investigated the induction and activation of HGF in various rat organs following burn …
Authors
Yamashita Y; Jeschke MG; Wolf SE
Journal
Cytokine, Vol. 12, No. 9, pp. 1293–1298
Publisher
Elsevier
Publication Date
September 2000
DOI
10.1006/cyto.2000.0719
ISSN
1043-4666