Journal article
Thermal Injury Activates the eEF2K‐Dependent eEF2 Pathway in Pediatric Patients
Abstract
BACKGROUND: Burn induces a hypermetabolic state characterized by alterations in protein metabolism, which is associated with increased morbidity and mortality. Eukaryotic elongation factor 2 (eEF2) plays a crucial role in regulating protein synthesis in many diseases, but whether it participates in burn-induced hypermetabolism is unclear. The aim of this study was to determine the expression of eEF2 and the upstream eEF2-inactivating kinase, …
Authors
Song J; Finnerty CC; Herndon DN; Kraft R; Boehning D; Brooks NC; Tompkins RG; Jeschke MG
Journal
Journal of Parenteral and Enteral Nutrition, Vol. 36, No. 5, pp. 596–602
Publisher
Wiley
Publication Date
September 2012
DOI
10.1177/0148607111422234
ISSN
0148-6071