Inhalation injury in severely burned children does not augment the systemic inflammatory response

IntroductionInhalation injury in combination with a severe thermal injury increases mortality. Alterations in inflammatory mediators, such as cytokines, contribute to the incidence of multi-organ failure and mortality. The aim of the present study was to determine the effect of inhalation injury on cytokine expression in severely burned children.MethodsThirty severely burned pediatric patients with inhalation injury and 42 severely burned …