Journal article
Recombinant Human Growth Hormone (rhGH) Downregulates Hepatocyte Growth Factor (HGF) in Burns
Abstract
INTRODUCTION: Hepatocyte growth factor (HGF) and recombinant human growth hormone (rhGH) have both been shown to increase albumin serum concentrations after major injury. However, the effect of rhGH on HGF production after injury is unknown. We postulated that rhGH effects constitutive protein concentrations by inducing HGF expression.
METHODS: In order to determine a dose response, 20 male Sprague-Dawley rats received three different …
Authors
Jeschke MG; Wolf SE; DebRoy MA; Jarrar D; Herndon DN
Journal
Journal of Surgical Research, Vol. 76, No. 1, pp. 11–16
Publisher
Elsevier
Publication Date
April 1998
DOI
10.1006/jsre.1998.5261
ISSN
0022-4804