Comparison of ventilation defects quantified by Technegas SPECT and hyperpolarized 129Xe MRI

Introduction: The ideal contrast agents for ventilation SPECT and MRI are Technegas and ¹²⁹Xe gas, respectively. Despite increasing interest in the clinical utility of ventilation imaging, these modalities have not been directly compared. Therefore, our objective was to compare the ventilation defect percent (VDP) assessed by Technegas SPECT and hyperpolarized ¹²⁹Xe MRI in patients scheduled to undergo lung cancer resection with and without …