Journal article
Comparative Efficacy of Infliximab Versus Tofacitinib for Inducing Remission in Biologic Naive Ulcerative Colitis: A Propensity Matched Study
Abstract
ObjectiveIn the absence of head-to-head clinical trials, indirect comparative studies are needed to help position therapies in ulcerative colitis (UC). We aimed to compare the efficacy of infliximab vs. tofacitinib for moderate-severe UC among biologic-naïve participants at post-induction.MethodsThis was a post-hoc analysis of patient-level data from four clinical trials including 659 biologic-naïve UC participants. We compared proportions of …
Authors
Wong ECL; Merat S; Monaco C; Dulai PS; Jairath V; Marshall JK; Reinisch W; Narula N
Journal
Digestive Diseases and Sciences, Vol. 68, No. 6, pp. 2635–2646
Publisher
Springer Nature
Publication Date
6 2023
DOI
10.1007/s10620-023-07956-8
ISSN
0163-2116