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Microbiota signatures and mucosal healing in the...
Journal article

Microbiota signatures and mucosal healing in the use of enteral nutrition therapy v. corticosteroids for the treatment of children with Crohn’s disease: a systematic review and meta-analysis

Abstract

Corticosteroids (CS) and exclusive and partial enteral nutrition (EEN and PEN) are effective therapies in paediatric Crohn's disease (CD). This systematic review of randomised controlled trials (RCT) and cohort studies analyses the impact of EEN/PEN v. CS on intestinal microbiota, mucosal healing as well as other clinically important outcomes, including clinical remission, relapse, adherence, adverse events and health-related quality of life …

Authors

Ding Z; Ninan K; Johnston BC; Moayyedi P; Sherlock M; Zachos M

Journal

British Journal Of Nutrition, Vol. 130, No. 8, pp. 1385–1402

Publisher

Cambridge University Press (CUP)

Publication Date

October 28, 2023

DOI

10.1017/s0007114523000405

ISSN

0007-1145