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Patterns of Failure after Stereotactic...
Conference

Patterns of Failure after Stereotactic Radiosurgery vs. Whole Brain Radiotherapy for Resected Brain Metastases: Central Imaging Review of the N107C/CEC.3 (Alliance) Phase III Clinical Trial

Abstract

Purpose/Objective(s) Whole brain radiotherapy (WBRT) has historically been the main instrument to decrease intracranial progression after resection of brain metastases. The previously reported NCCTG N107C/CEC.3 (Alliance) randomized phase III clinical trial of WBRT vs. stereotactic radiosurgery (SRS) demonstrated that overall survival did not significantly differ between arms, while SRS was associated with less cognitive decline than WBRT. …

Authors

Breen W; Dooley KE; Twohy E; Brown PD; Ballman K; Cerhan JH; Urbanic JJ; Whitton AC; Greenspoon J; Parney IF

Volume

114

Pagination

pp. 1063-1064

Publisher

Elsevier

Publication Date

December 2022

DOI

10.1016/j.ijrobp.2022.09.012

Conference proceedings

International Journal of Radiation Oncology • Biology • Physics

Issue

5

ISSN

0360-3016