Journal article
Population-based evaluation of the effectiveness of nirmatrelvir–ritonavir for reducing hospital admissions and mortality from COVID-19
Abstract
BACKGROUND: A randomized controlled trial involving a high-risk, unvaccinated population that was conducted before the Omicron variant emerged found that nirmatrelvir-ritonavir was effective in preventing progression to severe COVID-19. Our objective was to evaluate the effectiveness of nirmatrelvir-ritonavir in preventing severe COVID-19 while Omicron and its subvariants predominate.
METHODS: We conducted a population-based cohort study in …
Authors
Schwartz KL; Wang J; Tadrous M; Langford BJ; Daneman N; Leung V; Gomes T; Friedman L; Daley P; Brown KA
Journal
Canadian Medical Association Journal, Vol. 195, No. 6, pp. e220–e226
Publisher
Joule
Publication Date
February 13, 2023
DOI
10.1503/cmaj.221608
ISSN
0820-3946