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The regulation of protein synthesis in animal...
Journal article

The regulation of protein synthesis in animal cells by serum factors.

Abstract

We have investigated the regulation of protein synthesis in animal cells by serum factors. Withdrawal of serum from the medium of actively dividing Vero cells resulted in an immediate decline in the rate of peptide chain elongation (Hassell and Engelhardt, 1973). Assay of elongation factor I (EFI) activity in the post-ribosomal supernatant as well as that associated with the ribosomes revealed that serum deprivation resulted also in reduction …

Authors

Hassell JA; Engelhardt DL

Journal

Biochemistry, Vol. 15, No. 7, pp. 1375–1381

Publisher

American Chemical Society (ACS)

Publication Date

April 6, 1976

DOI

10.1021/bi00652a004

ISSN

0006-2960