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The structure and expression of two defective...
Journal article

The structure and expression of two defective adenovirus 2/simian virus 40 hybrids

Abstract

Two new defective adenovirus 2/simian virus 40 hybrids (Ad2+ D1 and Ad2 + D2) have been isolated from the population known as Ad2++ HEY (Lewis & Rowe, 1970). The structure of their genomes has been determined by analysis with restriction enzymes, hybridization and electron microscopy. The DNA of Ad2+D1 is almost equal in size to that of its helper, adenovirus 2. It contains an insertion of simian virus 40 (SV40) sequences 3.2 × 103 bases long …

Authors

Hassell JA; Lukanidin E; Fey G; Sambrook J

Journal

Journal of Molecular Biology, Vol. 120, No. 2, pp. 209–247

Publisher

Elsevier

Publication Date

April 1978

DOI

10.1016/0022-2836(78)90065-7

ISSN

0022-2836