Journal article
Homologous Recombination Between Transfected DNAs
Abstract
An extensive analysis of the fate and structure of polyomavirus-plasmid recombinant molecules transfected into Rat-1 cells has revealed that the DNA often becomes integrated within transformed cell DNA in a head-to-tail tandem arrangement. This occurs independently of the replicative capacity of the transforming DNA and is facilitated by the use of large quantities of DNA during transfection. These observations have led us to suggest that …
Authors
Pomerantz BJ; Naujokas M; Hassell JA
Journal
Molecular and Cellular Biology, Vol. 3, No. 9, pp. 1680–1685
Publisher
Taylor & Francis
Publication Date
September 1, 1983
DOI
10.1128/mcb.3.9.1680-1685.1983
ISSN
0270-7306