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Polyomavirus and simian virus 40 large T antigens...
Journal article

Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences

Abstract

The large T antigens of polyomavirus and simian virus 40 (SV40) recognize and bind to specific, noncoding DNA sequences which are located between the beginning of the early and late transcription units in their respective genomes. Each large T antigen binds to multiple sites within this intergenic DNA stretch. Polyomavirus large T antigen binds to at least two sites within its DNA, and SV40 large T antigen binds to three sites within SV40 DNA. …

Authors

Pomerantz BJ; Hassell JA

Journal

Journal of Virology, Vol. 49, No. 3, pp. 925–937

Publisher

American Society for Microbiology

Publication Date

March 1984

DOI

10.1128/jvi.49.3.925-937.1984

ISSN

0022-538X