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Deprescribing Anticholinergic and Sedative Drugs...
Journal article

Deprescribing Anticholinergic and Sedative Drugs to Reduce Polypharmacy in Frail Older Adults Living in the Community: A Randomized Controlled Trial

Abstract

BACKGROUND: Polypharmacy is associated with poor outcomes in older adults. Targeted deprescribing of anticholinergic and sedative medications may improve health outcomes for frail older adults. Our pharmacist-led deprescribing intervention was a pragmatic 2-arm randomized controlled trial stratified by frailty. We compared usual care (control) with the intervention of pharmacists providing deprescribing recommendations to general practitioners.

Authors

Jamieson H; Nishtala PS; Bergler HU; Weaver SK; Pickering JW; Ailabouni NJ; Abey-Nesbit R; Gullery C; Deely J; Gee SB

Journal

The Journals of Gerontology Series A, Vol. 78, No. 9, pp. 1692–1700

Publisher

Oxford University Press (OUP)

Publication Date

August 27, 2023

DOI

10.1093/gerona/glac249

ISSN

1079-5006