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A single dose of exercise stimulates skeletal...
Journal article

A single dose of exercise stimulates skeletal muscle mitochondrial plasticity in myotonic dystrophy type 1

Abstract

AIM: Myotonic dystrophy type 1 (DM1) is the second most common muscular dystrophy after Duchenne and is the most prevalent muscular dystrophy in adults. DM1 patients that participate in aerobic exercise training experience several physiological benefits concomitant with improved muscle mitochondrial function without alterations in typical DM1-specific disease mechanisms, which suggests that correcting organelle health is key to ameliorate the …

Authors

Mikhail AI; Manta A; Ng SY; Osborne AK; Mattina SR; Mackie MR; Ljubicic V

Journal

Acta Physiologica, Vol. 237, No. 4,

Publisher

Wiley

Publication Date

April 2023

DOI

10.1111/apha.13943

ISSN

1748-1708