Journal article
Association of common variants in the human eyes shut ortholog (EYS) with statin‐induced myopathy: Evidence for additional functions of EYS
Abstract
INTRODUCTION: Of the nearly 38 million people in the USA who receive statin therapy, 0.1-0.5% experience severe or life-threatening myopathic side effects.
METHODS: We performed a genome-wide association study (GWAS) in a group of patients with severe statin myopathy versus a statin-tolerant group to identify genetic susceptibility loci.
Authors
Isackson PJ; Ochs‐Balcom HM; Ma C; Harley JB; Peltier W; Tarnopolsky M; Sripathi N; Wortmann RL; Simmons Z; Wilson JD
Journal
Muscle & Nerve, Vol. 44, No. 4, pp. 531–538
Publisher
Wiley
Publication Date
October 2011
DOI
10.1002/mus.22115
ISSN
0148-639X