Journal article
Meta-analysis: effect of prophylactic hematopoietic colony-stimulating factors on mortality and outcomes of infection.
Abstract
BACKGROUND: Benefits of prophylactic hematopoietic colony-stimulating factors (CSFs) in adults and children receiving cancer chemotherapy or undergoing stem-cell transplantation (SCT) are unclear.
PURPOSE: To determine whether prophylactic CSFs decrease mortality, infections, and febrile neutropenia more than does placebo or no therapy in patients with cancer and in patients undergoing SCT.
Authors
Sung L; Nathan PC; Alibhai SMH; Tomlinson GA; Beyene J
Journal
Annals of Internal Medicine, Vol. 147, No. 6, pp. 400–411
Publisher
American College of Physicians
Publication Date
September 18, 2007
DOI
10.7326/0003-4819-147-6-200709180-00010
ISSN
1056-8751