Journal article
High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis
Abstract
OBJECTIVE: Psoriatic arthritis (PsA) has a clear familial predisposition, the major histocompatibility complex (MHC) region being the strongest genetic locus. The study primary objective was to identify single nucleotide polymorphisms (SNPs) independent of known human leucocyte antigen (HLA) alleles within the MHC region that are associated with PsA using a high-density SNP map.
METHOD: In all, 914 samples were assessed, including 427 PsA cases …
Authors
Rahman P; Roslin NM; Pellett FJ; Lemire M; Greenwood CMT; Beyene J; Pope A; Peddle L; Paterson AD; Uddin M
Journal
Annals of the Rheumatic Diseases, Vol. 70, No. 4, pp. 690–694
Publisher
Elsevier
Publication Date
April 2011
DOI
10.1136/ard.2010.133561
ISSN
0003-4967