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Anthracyclines during induction therapy in acute...
Journal article

Anthracyclines during induction therapy in acute myeloid leukaemia: a systematic review and meta‐analysis

Abstract

This systematic review and meta-analysis compared the efficacy of different anthracyclines and anthracycline dosing schedules for induction therapy in acute myeloid leukaemia in children and adults younger than 60 years of age. Twenty-nine randomized controlled trials were eligible for inclusion in the review. Idarubicin (IDA), in comparison to daunorubicin (DNR), reduced remission failure rates (risk ratio (RR) 0·81; 95% confidence interval …

Authors

Teuffel O; Leibundgut K; Lehrnbecher T; Alonzo TA; Beyene J; Sung L

Journal

British Journal of Haematology, Vol. 161, No. 2, pp. 192–203

Publisher

Wiley

Publication Date

April 2013

DOI

10.1111/bjh.12233

ISSN

0007-1048