Journal article
Calculation of singlet oxygen dose from photosensitizer fluorescence and photobleaching during mTHPC photodynamic therapy of MLL cells.
Abstract
Predicting the therapeutic outcome of photodynamic therapy (PDT) requires knowledge of the amount of cytoxic species generated. An implicit approach to assessing PDT efficacy has been proposed where changes in photosensitizer (PS) fluorescence during treatment are used to predict treatment outcome. To investigate this, in vitro experiments were performed in which Mat-LyLu cells were incubated in meta-tetra(hydroxyphenyl)chlorin (mTHPC) and then …
Authors
Dysart JS; Singh G; Patterson MS
Journal
Photochemistry and Photobiology, Vol. 81, No. 1, pp. 196–205
Publisher
Wiley
Publication Date
2004
DOI
10.1562/2004-07-23-ra-244
ISSN
0031-8655