Journal article
Simple Photodynamic Therapy Dose Models Fail to Predict the Survival of MLL Cells After HPPH–PDT In Vitro
Abstract
Fluorescence photobleaching, photodynamic therapy (PDT) oxygen consumption and clonogenic cell survival were investigated during 2-(1-hexyloxethyl)-2-devinyl pyropheophoribde-a (HPPH) PDT of MAT-LyLu cells in vitro. Cells were incubated with HPPH concentrations of 0.24, 1.2, 3.6 or 12 microm for 4 h and then treated with 650 nm light under oxygenated and hypoxic conditions. Fluorescence spectra were acquired during treatment and photobleaching …
Authors
Weston MA; Patterson MS
Journal
Photochemistry and Photobiology, Vol. 85, No. 3, pp. 750–759
Publisher
Wiley
Publication Date
May 2009
DOI
10.1111/j.1751-1097.2008.00494.x
ISSN
0031-8655