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Bioluminescence Tomography–Guided Radiation...
Journal article

Bioluminescence Tomography–Guided Radiation Therapy for Preclinical Research

Abstract

PURPOSE: In preclinical radiation research, it is challenging to localize soft tissue targets based on cone beam computed tomography (CBCT) guidance. As a more effective method to localize soft tissue targets, we developed an online bioluminescence tomography (BLT) system for small-animal radiation research platform (SARRP). We demonstrated BLT-guided radiation therapy and validated targeting accuracy based on a newly developed reconstruction …

Authors

Zhang B; Wang KK-H; Yu J; Eslami S; Iordachita I; Reyes J; Malek R; Tran PT; Patterson MS; Wong JW

Journal

International Journal of Radiation Oncology • Biology • Physics, Vol. 94, No. 5, pp. 1144–1153

Publisher

Elsevier

Publication Date

April 2016

DOI

10.1016/j.ijrobp.2015.11.039

ISSN

0360-3016