Journal article
Left/right nigrostriatal asymmetry in susceptibility to neurotoxic dopamine depletion with 6-hydroxydopamine in rats
Abstract
Male Sprague-Dawley rats were investigated for the existence of a left/right hemispheric population asymmetry in the extent of striatal dopamine depletion following unilateral lesions with 6-hydroxydopamine (6-OHDA) in the left or right substantial nigra. Four doses of 6-OHDA were employed (with left and right lesion groups at each dose). Analysis of striatal dopamine depletion revealed significant main effects not only for dose of 6-OHDA, but …
Authors
Sullivan RM; Szechtman H
Journal
Neuroscience Letters, Vol. 170, No. 1, pp. 83–86
Publisher
Elsevier
Publication Date
March 1994
DOI
10.1016/0304-3940(94)90244-5
ISSN
0304-3940