Journal article
Compulsive checking behavior of quinpirole-sensitized rats as an animal model of Obsessive-Compulsive Disorder(OCD): form and control
Abstract
BackgroundA previous report showed that the open field behavior of rats sensitized to the dopamine agonist quinpirole satisfies 5 performance criteria for compulsive checking behavior. In an effort to extend the parallel between the drug-induced phenomenon and human obsessive-compulsive disorder (OCD), the present study investigated whether the checking behavior of quinpirole rats is subject to interruption, which is an attribute characteristic …
Authors
Szechtman H; Eckert MJ; Tse WS; Boersma JT; Bonura CA; McClelland JZ; Culver KE; Eilam D
Journal
BMC Neuroscience, Vol. 2, No. 1,
Publisher
Springer Nature
Publication Date
2001
DOI
10.1186/1471-2202-2-4
ISSN
1471-2202