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Characterization and regulation of the...
Journal article

Characterization and regulation of the insulin-like growth factor (IGF) system in the zebrafish (Danio rerio) ovary

Abstract

Locally produced peptide hormones play an important role in the paracrine/autocrine regulation of ovarian development. The insulin-like growth factor (IGF) system is one family of local factors that has not been well studied in the ovary of fish. This study characterized the zebrafish (Danio rerio) ovarian IGF system, its spatial and temporal expression and regulation by gonadotropins and steroids. Three ligands (igf2a, igf2b, igf3) and two …

Authors

Nelson SN; Van Der Kraak G

Journal

General and Comparative Endocrinology, Vol. 168, No. 1, pp. 111–120

Publisher

Elsevier

Publication Date

August 2010

DOI

10.1016/j.ygcen.2010.04.020

ISSN

0016-6480