Journal article
Direct measurement of high‐energy phosphate compounds in patients with neuromuscular disease
Abstract
Several neuromuscular disorders are associated with reductions in intramuscular adenosine triphosphate (ATP) and/or phosphocreatine (PCr). These alterations have been primarily characterized using (31)P-magnetic resonance spectroscopy ((31)P-MRS). We prospectively measured total creatine, PCr, and ATP in muscle biopsies from 81 patients: normal controls (n = 33), mitochondrial cytopathy (n = 8), neuropathic (n = 3), dystrophy/congenital …
Authors
Tarnopolsky MA; Parise G
Journal
Muscle & Nerve, Vol. 22, No. 9, pp. 1228–1233
Publisher
Wiley
Publication Date
September 1999
DOI
10.1002/(sici)1097-4598(199909)22:9<1228::aid-mus9>3.0.co;2-6
ISSN
0148-639X