Journal article
Analysis and Parametric Optimization of 1H Off-Resonance Relaxation NMR Experiments Designed to Map Polypeptide Self-Recognition and Other Noncovalent Interactions
Abstract
The measurement of 1H off-resonance nonselective relaxation rates (R(theta,ns)) has been recently proposed as an effective method to probe peptide self-recognition, opening new perspectives in the understanding of the prefibrillization oligomerization processes in amylodogenesis. However, a full analysis and parametric optimization of the NMR experiments designed to measure R(theta,ns) relaxation rates is still missing. Here we analyze the …
Authors
Milojevic J; Esposito V; Das R; Melacini G
Journal
The Journal of Physical Chemistry B, Vol. 110, No. 41, pp. 20664–20670
Publisher
American Chemical Society (ACS)
Publication Date
October 1, 2006
DOI
10.1021/jp063194z
ISSN
1520-6106