Journal article
Progenitor cell‐derived basophils: A novel barcoded passive degranulation assay in allergic diseases
Abstract
BACKGROUND: Effector cells assays provide an overall measure of responsiveness to allergen, but the lack of reliable and high-throughput assays limits the clinical utility. We aimed to develop a high-throughput basophil activation test based on human progenitor cell-derived basophils (PCB) and investigate the role of PCB activation test (PCBAT) in allergic diseases.
METHODS: Progenitor cell-derived basophils were differentiated from CD34+ …
Authors
Wu J; Bahri R; Tsoumani M; Semic‐Jusufagic A; Murray CS; Custovic A; Guibas GV; Bennett M; Wang R; Gauvreau G
Journal
Clinical & Experimental Allergy, Vol. 53, No. 4, pp. 405–416
Publisher
Wiley
Publication Date
April 2023
DOI
10.1111/cea.14251
ISSN
0954-7894