Journal article
Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways s⃞
Abstract
Scavenger receptor, class B, type I (SR-BI) mediates binding and internalization of a variety of lipoprotein and nonlipoprotein ligands, including HDL. Studies in genetically engineered mice revealed that SR-BI plays an important role in HDL reverse cholesterol transport and protection against atherosclerosis. Understanding how SR-BI's function is regulated may reveal new approaches to therapeutic intervention in atherosclerosis and heart …
Authors
Zhang Y; Ahmed AM; McFarlane N; Capone C; Boreham DR; Truant R; Igdoura SA; Trigatti BL
Journal
Journal of Lipid Research, Vol. 48, No. 2, pp. 405–416
Publisher
Elsevier
Publication Date
February 2007
DOI
10.1194/jlr.m600326-jlr200
ISSN
0022-2275