Journal article
Cholesterol depletion inhibits fatty acid uptake without affecting CD36 or caveolin-1 distribution in adipocytes
Abstract
Caveolin-1 and CD36 are plasma membrane fatty acid binding proteins that participate in adipocyte fatty acid uptake and metabolism. Both are associated with cholesterol-enriched caveolae/lipid rafts in the plasma membrane that are important for long chain fatty acid uptake. Depletion of plasma membrane cholesterol reversibly inhibited oleate uptake by adipocytes without altering the amount or the cell surface distribution of either caveolin-1 …
Authors
Covey SD; Brunet RH; Gandhi SG; McFarlane N; Boreham DR; Gerber GE; Trigatti BL
Journal
Biochemical and Biophysical Research Communications, Vol. 355, No. 1, pp. 67–71
Publisher
Elsevier
Publication Date
March 2007
DOI
10.1016/j.bbrc.2007.01.135
ISSN
0006-291X