Journal article
The Adaptive Response and Protection against Heritable Mutations and Fetal Malformation
Abstract
There are a number of studies that show radiation can cause heritable mutations in the offspring of irradiated organisms. These "germ-line mutations" have been shown to occur in unique sequences of DNA called "minisatellite loci". The high frequencies of spontaneous and induced mutations at minisatellite loci allow mutation induction to be measured at low doses of exposure in a small population, making minisatellite mutation a powerful tool to …
Authors
Boreham DR; Dolling J-A; Somers C; Quinn J; Mitchel REJ
Journal
Dose-Response, Vol. 4, No. 4,
Publisher
SAGE Publications
Publication Date
October 1, 2006
DOI
10.2203/dose-response.06-104.boreham
ISSN
1540-1421