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Synthesis, Characterisation, and Biodistribution...
Journal article

Synthesis, Characterisation, and Biodistribution of Radioiodinated C‐Hydroxy‐Carboranes

Abstract

The synthesis, radiolabelling and biodistribution of iodinated C-hydroxy-nido-carborane ligands is described. Microwave heating by using NaF in aqueous ethanol was used to prepare {sodium [7-hydroxy-7,8-dicarba-nido-undecaborate], nido-carboranol} and {sodium [7-hydroxy-7,8-dicarba-nido-undecaborate-8-carboxylic acid], nido-salborin} in 97 and 90 % yield, respectively. Radioiodination of these nido-carboranes was completed by using both (125)I …

Authors

El‐Zaria ME; Janzen N; Blacker M; Valliant JF

Journal

Chemistry - A European Journal, Vol. 18, No. 35, pp. 11071–11078

Publisher

Wiley

Publication Date

August 27, 2012

DOI

10.1002/chem.201200833

ISSN

0947-6539