Falling Third-Trimester Insulin Requirements and Adverse Pregnancy Outcomes

INTRODUCTION: There is conflicting evidence on whether falling insulin requirements in the third-trimester are associated with adverse pregnancy outcomes. Our objective was to systematically review the literature to determine the association between a ≥15 percent fall in insulin dose (PFID) and adverse pregnancy outcomes. METHODS: We searched Medline, Embase and PubMed from inception until October 2016 for English language articles describing …