Journal article
Menin Links the Stress Response to Genome Stability in Drosophila melanogaster
Abstract
BACKGROUND: The multiple endocrine neoplasia type I gene functions as a tumor suppressor gene in humans and mouse models. In Drosophila melanogaster, mutants of the menin gene (Mnn1) are hypersensitive to mutagens or gamma irradiation and have profound defects in the response to several stresses including heat shock, hypoxia, hyperosmolarity and oxidative stress. However, it is not known if the function of menin in the stress response …
Authors
Papaconstantinou M; Pepper AN; Wu Y; Kasimer D; Westwood T; Campos AR; Bédard P-A
Journal
PLOS ONE, Vol. 5, No. 11,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0014049
ISSN
1932-6203