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Contribution of Common Genetic Variants to Risk of...
Journal article

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke

Abstract

BACKGROUND AND OBJECTIVES: Current genome-wide association studies of ischemic stroke have focused primarily on late-onset disease. As a complement to these studies, we sought to identify the contribution of common genetic variants to risk of early-onset ischemic stroke. METHODS: We performed a meta-analysis of genome-wide association studies of early-onset stroke (EOS), ages 18-59 years, using individual-level data or summary statistics in …

Authors

Jaworek T; Xu H; Gaynor BJ; Cole JW; Rannikmae K; Stanne TM; Tomppo L; Abedi V; Amouyel P; Armstrong ND

Journal

Neurology, Vol. 99, No. 16, pp. e1738–e1754

Publisher

Wolters Kluwer

Publication Date

October 18, 2022

DOI

10.1212/wnl.0000000000201006

ISSN

0028-3878