Journal article
Cost-Effectiveness of Polygenic Risk Scores to Guide Statin Therapy for Cardiovascular Disease Prevention
Abstract
BACKGROUND: Atherosclerotic cardiovascular diseases (CVDs) are leading causes of death despite effective therapies and result in unnecessary morbidity and mortality throughout the world. We aimed to investigate the cost-effectiveness of polygenic risk scores (PRS) to guide statin therapy for Canadians with intermediate CVD risk and model its economic outlook.
METHODS: This cost-utility analysis was conducted using UK Biobank prospective cohort …
Authors
Kiflen M; Le A; Mao S; Lali R; Narula S; Xie F; Paré G
Journal
Circulation Genomic and Precision Medicine, Vol. 15, No. 5,
Publisher
Wolters Kluwer
Publication Date
10 2022
DOI
10.1161/circgen.121.003423
ISSN
1942-325X