Journal article
A cross‐species validation of single‐beat metrics of cardiac contractility
Abstract
The assessment of left ventricular (LV) contractility in animal models is useful in various experimental paradigms, yet obtaining such measures is inherently challenging and surgically invasive. In a cross-species study using small and large animals, we comprehensively tested the agreement and validity of multiple single-beat surrogate metrics of LV contractility against the field-standard metrics derived from inferior vena cava occlusion …
Authors
Ahmadian M; Williams AM; Mannozzi J; Konecny F; Hoiland RL; Wainman L; Erskine E; Duffy J; Manouchehri N; So K
Journal
The Journal of Physiology, Vol. 600, No. 22, pp. 4779–4806
Publisher
Wiley
Publication Date
11 2022
DOI
10.1113/jp283319
ISSN
0022-3751